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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MMEL1
All Species:
11.82
Human Site:
S466
Identified Species:
23.64
UniProt:
Q495T6
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q495T6
NP_258428.2
779
89367
S466
A
F
P
G
D
S
K
S
M
V
R
E
L
I
D
Chimpanzee
Pan troglodytes
XP_001150860
781
89158
S468
A
F
P
G
D
S
K
S
M
V
R
E
L
I
D
Rhesus Macaque
Macaca mulatta
XP_001105708
750
85452
H438
A
F
A
G
E
S
K
H
V
V
E
D
L
I
A
Dog
Lupus familis
XP_546737
807
92419
D494
A
F
P
G
D
S
K
D
A
V
R
E
L
I
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLI3
765
88681
S452
A
F
S
K
D
S
K
S
T
V
R
E
L
I
E
Rat
Rattus norvegicus
P0C1T0
774
89178
S461
A
F
S
K
D
S
K
S
I
V
S
E
L
I
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233077
749
86047
R436
T
F
A
G
E
S
K
R
M
V
Q
D
L
I
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_689191
755
86752
R442
T
F
S
G
N
S
K
R
M
V
G
E
L
I
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_511056
849
96515
E539
N
F
N
Q
E
S
K
E
V
A
L
E
M
I
H
Honey Bee
Apis mellifera
XP_392502
776
89056
E466
N
F
N
H
E
S
K
E
T
A
L
E
M
I
R
Nematode Worm
Caenorhab. elegans
O16796
848
97043
H536
H
F
Q
E
S
D
K
H
E
A
L
R
M
I
M
Sea Urchin
Strong. purpuratus
XP_781407
763
86739
N454
N
F
A
G
E
S
K
N
N
T
L
R
M
I
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.9
50.8
82.6
N.A.
77
77.6
N.A.
N.A.
66.2
N.A.
59.9
N.A.
39
40.5
35
38.1
Protein Similarity:
100
97.1
72
89
N.A.
88.6
88.8
N.A.
N.A.
81.6
N.A.
77.6
N.A.
55.9
59.8
54.1
58.5
P-Site Identity:
100
100
53.3
86.6
N.A.
73.3
66.6
N.A.
N.A.
60
N.A.
60
N.A.
33.3
33.3
20
33.3
P-Site Similarity:
100
100
73.3
86.6
N.A.
80
80
N.A.
N.A.
80
N.A.
66.6
N.A.
53.3
46.6
26.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
0
25
0
0
0
0
0
9
25
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
42
9
0
9
0
0
0
17
0
0
34
% D
% Glu:
0
0
0
9
42
0
0
17
9
0
9
67
0
0
17
% E
% Phe:
0
100
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
59
0
0
0
0
0
0
9
0
0
0
0
% G
% His:
9
0
0
9
0
0
0
17
0
0
0
0
0
0
9
% H
% Ile:
0
0
0
0
0
0
0
0
9
0
0
0
0
100
0
% I
% Lys:
0
0
0
17
0
0
100
0
0
0
0
0
0
0
17
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
34
0
67
0
0
% L
% Met:
0
0
0
0
0
0
0
0
34
0
0
0
34
0
9
% M
% Asn:
25
0
17
0
9
0
0
9
9
0
0
0
0
0
0
% N
% Pro:
0
0
25
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
9
9
0
0
0
0
0
0
9
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
17
0
0
34
17
0
0
9
% R
% Ser:
0
0
25
0
9
92
0
34
0
0
9
0
0
0
0
% S
% Thr:
17
0
0
0
0
0
0
0
17
9
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
17
67
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _